Antonio Trejo Osorio (Ixmiquilpan, Hidalgo, 1922 - 1986) was a painter born into a semi-rural family. He studied at the Academia de San Carlos (San Carlos Academy of Fine Arts), where he was taught by artists such as José Chávez Morado and Alfredo Zalce. Between 1943 and 1947, he pursued his artistic studies at the Escuela Nacional de Artes Plásticas (National School of Fine Arts). In 1949, he exhibited his work at the 2nd Annual Painting and Sculpture Salon organized by the Sociedad para el Impulso de las Artes Plásticas (Society for the Promotion of Fine Arts) at the Galería de Arte Moderno (Gallery of Modern Art), owned by Francisco Rodríguez Caracalla. 

En 1952, he participated in the exhibition of paintings and engravings organized by the Frente Nacional de Artes Plásticas (National Front of Fine Arts). Later, he moved to Michoacán, where he taught at the Escuela de Bellas Artes (School of Fine Arts) in Morelia.